Publications


List of peer-reviewed publications

2025 – 2026

SlitNET: A Deep Learning Enabled Spectrometer Slit

Y. Zhang, C. Bench, P. Surendranathan, M. S. Bergholt

Analytical Chemistry, Vol. 97 / Issue 18

2024

Label-free 3D molecular imaging of living tissues using Raman Spectral Projection Tomography

E. Stepula, A. R. Walther, M. Jensen, D. H. Mehrota, M. U. Yan, S. V. Pedersen, V. Kumar, E. Gentleman, M. B. Albro, M. A. B. Hedegaard, M. S. Bergholt

Nature Communications 15, Article no. 7717 (2024)

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Spatially‐Resolved Organoid Transfection by Porous Silicon‐Mediated Optoporation

C. Spiteri, V. Caprettini, Y. Wang, S. Dominguez‐Gil, M. Kaasalainen, C. Wang, D. A. Martella, S. McLennan, P. Vashisth, M. Gary‐Bobo, C. Nguyen, M. S. Bergholt, J‐O. Durand, F. Cunin, C. Chiappini

Advanced Materials 2024, 2407650

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Lithiated porous silicon nanowires stimulate periodontal regeneration

M. Kaasalainen, R. Zhang, P. Vashisth, A. Birjandi, M. S'ari, D. Martella, M. Isaacs, E. Makila, C. Wang, E. Moldenhauer, P. Clarke, A. Pinna, V. Caprettini, A. Morrell, O. Addison, X. Zhang, M. S. Bergholt, K. Al-Jamal, A. Angelova-Volponi, J. Salonen, N. Hondow, P. Sharpe, E. Gentleman, S. Mustfa, X. Zhang, D. Brauer, C. Chiappini

Nature Communications 15, 487 (2024)

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A comparative study of analytical models of diffuse reflectance in homogeneous biological tissues

A. Bahl, S. Segaud, Y. Xie, J. Shapey, M. S. Bergholt, T. Vercauteren

Journal of Biophotonics, 2024; e202300536

SOL3D: Soft-lithography on 3D vat polymerised moulds for fast, versatile, and accessible high-resolution fabrication of customised multiscale cell culture devices

C. Hagemann, M. C. D. Bailey, E. Carraro, V. M. Lionello, N. Khokhar, P. Suklai, C. Moreno-Gonzalez, K. O'Toole, G. Konstantinou, S. Joshi, E. Giagnorio, M. S. Bergholt, A. Imbert, F. S. Tedesco, A. Serio

PLOS Biology (2024)

2023

Opto-lipidomics of Tissues Advanced Science

M. Jensen, S. Liu, E. Stepula, D. Martella, A. A. Birjandi, K. Farrell-Dillon, K. L. A. Chan, M. Parsons, C. Chiappini, S. J. Chapple, G. E. Mann, T. Vercauteren, V. Abbate, M. S. Bergholt

Advanced Science, 2023, 2302962

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Lightfield hyperspectral imaging in neuro-oncology surgery: an IDEAL 0 and 1 study

A. O. MacCormac, P. Noonan, M. Janatka, C. C. Horgan, A. Bahl, J. Qiu, M. Elliott, T. Trotouin, J. Jacobs, S. Patel, M. S. Bergholt, K. Ashkan, S. Ourselin, M. Ebner, T. Vercauteren, J. Shapey

Frontiers in Neuroscience, 18 September 2023, Volume 17

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Synthetic white balancing for intra-operative hyperspectral imaging

A. Bahl, C. C. Horgan, M. Janatka, O. J. MacCormac, P. Noonan, Y. Xie, J. Qiu, N. Cavalcanti, P. Fürnstahl, M. Ebner, M. S. Bergholt, J. Shapey, T. Vercauteren

Journal of Medical Imaging, Vol. 10, Issue 4, 046001 (July 2023)

In Vivo Longitudinal Monitoring of Disease Progression in Inflammatory Arthritis Animal Models Using Raman Spectroscopy

A. R. Walther, E. Stepula, N. Ditzel, M. Kassem, M. S. Bergholt, M. A. B. Hedegaard

Analytical Chemistry 2023, 95, 7, 3720–3728

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2022

spectrai: A deep learning framework for spectral data

C. C. Horgan, M. S. Bergholt

Journal of Spectral Imaging, a7, 11, 2022

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Hybrid confocal Raman endomicroscopy for morpho-chemical tissue characterization

C. C. Horgan, M. Jensen, C. Chiappini, T. Vercauteren, R. Cook, M. S. Bergholt

Biomedical Optics Express (2022)

2021

High-throughput molecular imaging via deep learning enabled Raman spectroscopy

C. C. Horgan, M. Jensen, A. Nagelkerke, J.-P. St-Pierre, T. Vercauteren, M. M. Stevens, M. S. Bergholt

Analytical Chemistry, 93(48), 15850–15860, 2021

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Raman needle arthroscopy for in vivo molecular assessment of cartilage

K. R. Kroupa, M. I. Wu, J. Zhang, M. Jensen, W. Wong, J. B. Engiles, M. W. Grinstaff, B. D. Snyder, M. S. Bergholt, M. B. Albro

Journal of Orthopaedic Research, 2021; 1–11

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Image-guided Raman spectroscopy probe-tracking for tumor margin delineation

C. C. Horgan, M. S. Bergholt, M. Z. Thin, A. Nagelkerke, R. Kennedy, T. L. Kalber, D. J. Stuckey, M. M. Stevens

Journal of Biomedical Optics, 26(3), 036002, 2021

Integrated photodynamic Raman theranostic system for cancer diagnosis, treatment, and post-treatment molecular monitoring

C. C. Horgan, M. S. Bergholt, A. Nagelkerke, M. Z. Thin, I. J. Pence, U. Kauscher, T. L. Kalber, D. J. Stuckey, M. M. Stevens

Theranostics 2021; 11(4): 2006–2019

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2020

In vivo biomolecular imaging of zebrafish embryos using confocal Raman spectroscopy

H. Høgset, C. C. Horgan, J. P. K. Armstrong, M. S. Bergholt, V. Torraca, Q. Chen, T. J. Keane, L. Bugeon, M. J. Dallman, S. Mostowy, M. M. Stevens

Nature Communications, 2020 Nature Comms

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Complementary techniques to analyse pericellular matrix formation by human MSC within hyaluronic acid hydrogels

C. Salzlechner, A. R. Walther, S. Schell, N. G. Merrild, T. Haghighi, I. Huebscher, G. Undt, K. Fan, M. S. Bergholt, M. A. B. Hedegaard, E. Gentleman

Materials Advances, 2020

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Bioenergetic-active materials enhance tissue regeneration by modulating cellular metabolic state

H. Liu, Y. Du, J.-P. St-Pierre, M. S. Bergholt, H. Autefage, J. Wang, M. Cai, G. Yang, M. M. Stevens, S. Zhang

Science Advances, Vol. 6, no. 13, eaay7608 (2020)

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Multiplexed polarized hypodermic Raman needle probe for biostructural analysis of articular cartilage

M. Jensen, C. C. Horgan, T. Vercauteren, M. B. Albro, M. S. Bergholt

Optics Letters, Vol. 45, Issue 10, pp. 2890–2893 (2020)

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Molecular imaging of extracellular vesicles in vitro via Raman metabolic labelling

C. C. Horgan, A. Nagelkerke, T. E. Whittaker, V. Nele, L. Massi, U. Kauscher, J. Penders, M. S. Bergholt, S. R. Hood, M. M. Stevens

Journal of Materials Chemistry B, 2020

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Surface enhanced Raman scattering artificial nose for high dimensionality fingerprinting

N. Kim, M. R. Thomas, M. S. Bergholt, I. J. Pence, H. Seong, P. Charchar, N. Todorova, A. Nagelkerke, A. Belessiotis-Richards, D. J. Payne, A. Gelmi, I. Yarovsky, M. M. Stevens

Nature Communications, 11, 207 (2020)

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2019

Raman spectroscopy: Guiding light for the extracellular matrix

M. S. Bergholt, A. Serio, M. B. Albro

Frontiers in Bioengineering and Biotechnology, 7, 41, 2019

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2018

Single particle automated Raman trapping analysis

J. Penders, I. J. Pence, C. Horgan, M. S. Bergholt, C. Wood, A. Najer, U. Kauscher, A. Nagelkerke, M. M. Stevens

Nature Communications, 9, 4256, 2018

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Raman Spectroscopic Imaging for Quantification of Depth-Dependent and Local Heterogeneities in Native and Engineered Cartilage

M. B. Albro, M. S. Bergholt, J. P. St-Pierre, A. Vinals Guitart, H. Zlotnick, E. Evita, M. M. Stevens

Nature Publishing Journals: Regenerative Medicine, 3, 3, 2018

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Correlated Heterospectral Lipidomics for Biomolecular Profiling of Remyelination in Multiple Sclerosis ACS Central Science

M. S. Bergholt, A. Serio, J. S. McKenzie, A. Boyd, R. F. Soares, J. Tillner, C. Chiappini, V. Wu, A. Dannhorn, Z. Takats, A. Williams, M. M. Stevens

ACS Central Science, 4(1), 39–51, 2018

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2017

Raman spectroscopy imaging reveals interplay between atherosclerosis and medial calcification in human aorta

A. Y. F. You, M. S. Bergholt, J. P. St-Pierre, A. H. Chester, M. H. Yacoub, S. Bertazzo, M. M. Stevens

Science Advances, 3(12), e1701156, 2017

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Full Publication Record

For a complete and up-to-date list of all publications, including conference proceedings, preprints, and book chapters, visit Google Scholar.

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